Pollution is a key driver affecting biodiversity loss. Part of the pollution comes from essential human activities, such as health care and food production through the use of pharmaceutical products (PP). Aquatic environments are quite vulnerable to PP pollution, both structure and functionality. Consequently, as traditional wastewater treatment plants (WWTP) cannot eliminate PP completely, and PP consumption increases steadily, there are resultant health threats to humans and ecosystems. However, some treatments are expensive and energy demanding. NbS, harnessing natural processes and ecosystems functioning, can help addressing the challenge our society is facing.